
Know What Causes High Creatinine and When to Worry
High creatinine is often a false alarm—creatine, protein, or dehydration can raise it without harming your kidneys. Here's how to tell benign from serious.
Sameer Patel is the founder and editor of My Medicine Advisor. He is not a doctor or medical professional — before starting this site he worked in banking, and he now researches and edits health information full-time.
He started My Medicine Advisor to make clear, well-sourced health information freely available to anyone. Every article is researched from recognised authorities such as the WHO, CDC, NIH, and NICE, drafted with the help of AI tools, and edited by hand, with sources linked so readers can check them. The calculators on the site use established, published formulas, each one named so you can look it up yourself.
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High creatinine is often a false alarm—creatine, protein, or dehydration can raise it without harming your kidneys. Here's how to tell benign from serious.

High ALT flags liver-cell stress, but how high matters. Here's the graded scale from borderline to massive, what usually causes it, and when it's urgent.

Reading a comprehensive metabolic panel: doctors read all 14 numbers as a pattern, and 1 in 20 healthy people fall outside a normal range by design.

Your comprehensive metabolic panel normal range spans 14 values, each with its own numbers. See the full chart and what one out-of-range result means.

Total protein and calcium ride on albumin, which binds 40–45% of it. In 22,658 patients, the standard correction was right only 58.7% of the time.

High glucose on a CMP can also read falsely low — glucose falls 5–7% per hour in an unseparated tube. Here's what your number really tells you.

CMP electrolytes hide a quiet problem: a potassium of 3.6 is low by MedlinePlus and normal by another widely used reference. Only your lab's range counts.

Liver markers on a CMP are read together, never alone. Clinicians classify liver injury by comparing ALT against ALP — and the ratio changes the answer.

Your CMP checks kidney function with three markers, and BUN alone can rise from simple dehydration. Here is how the three are read together.

Abnormal CMP results are common and rarely mean disease alone. See what flagged glucose, kidney, and liver values signal—and when to seek care.